Types and Causes of Amyloidosis
When an abnormal protein, amyloid, gets deposited in the organs or tissues, the condition is known as amyloidosis. When such a condition is developed, the functions of the affected tissue or organ are disrupted as well. Amyloidosis is a serious condition and can cause health problems, which could be life-threatening, causing failure of organs. Amyloid deposits can be the result of several different proteins; it has been associated with severe health problems. The type of amyloidosis depends on the place where the protein has been collected. The deposition of amyloid could be all over the body or in one place. Various types of amyloidosis and their associated causes: 1. Light chain amyloidosis (AL) The immunoglobulin light chain amyloidosis (AL) is one of the common types of amyloidosis. This is also known as primary amyloidosis. The amyloid light chain is a type of protein responsible for this type of amyloidosis. There is no known cause for this type of amyloidosis; however, it develops when the marrow of the bone forms abnormal antibodies that cannot be broken down. This type of amyloidosis is associated with a type of blood cancer known as multiple myeloma. This can affect the nerves, intestines, liver, heart, and kidneys.